Retroviruses PDF
By:Reinhard Kurth,Norbert Bannert
Published on 2010-01-01 by Horizon Scientific Press
Retroviruses comprise a diverse family of enveloped RNA viruses, remarkable for their use of reverse transcription of viral RNA into linear double stranded DNA during replication and the subsequent integration of this DNA into the genome of the host cell. Members of this family include important pathogens such as HIV-1, feline leukemia, and several cancer-causing viruses. However, interest in these viruses extends beyond their disease-causing capabilities. For example, research in this area led to the discovery of oncogenes, a major advance in the field of cancer genetics. Studies of retroviruses have contributed greatly to our understanding of mechanisms that regulate eukaryotic gene expression. In addition, retroviruses are proving to be valuable research tools in molecular biology and have been used successfully in gene therapy (e.g. to treat X-linked severe combined immunodeficiency). Written by the top retroviral specialists, this book reviews the genomics, molecular biology, and pathogenesis of these important viruses, comprehensively covering all the recent advances. Topics include: host and retroelement interactions * endogenous retroviruses * retroviral proteins and genomes * viral entry and uncoating * reverse transcription and integration * transcription * splicing and RNA transport * pathogenesis of oncoviral infections * pathogenesis of immunodeficiency virus infections * retroviral restriction factors, molecular vaccines, and correlates of protection * gammaretroviral and lentiviral vectors * non-primate mammalian and fish retroviruses * simian exogenous retroviruses * and HTLV and HIV. It is essential reading for every retrovirologist and it is a recommended text for all virology and molecular biology laboratories.
This Book was ranked at 6 by Google Books for keyword Molecular.
Book ID of Retroviruses's Books is Vx3HbMRDj1IC, Book which was written byReinhard Kurth,Norbert Bannerthave ETAG "Ano0BJLc6cM"
Book which was published by Horizon Scientific Press since 2010-01-01 have ISBNs, ISBN 13 Code is 9781904455554 and ISBN 10 Code is 1904455557
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Book which have "454 Pages" is Printed at BOOK under CategoryScience
Book was written in en
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